Mylab HLA B27 Detection Kit

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Mylab HLA B27 Detection Kit

Human leukocyte antigen (HLA) B27  is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6. The human leucocyte antigen (HLA) B*27 is strongly associated with the spondyloarthropathies (SpA’s).  

HLA-B*27 is found in 90-95% of ankylosing spondylitis (AS) patients and also lesser frequency in forms of psoriatic arthritis and reactive arthritis. HLA-B*27 may have a direct role in the pathogenesis of SpA. There are more than 50 subtypes of HLA-B27 identified which mostly differ by only a small number of nucleotides. Allele specific PCR offers excellent specificity and sensitivity for HLA-B*27 genotype. 

Mylab Lifesolutions HLAB*27 Detection test is an in vitro diagnostic test for the detection of HLAB*27 genotypes as an aid to diagnosis in the evaluation of patients with suspected ankylosing spondylitis by allele specific real time PCR.

Kit Features

  • Highly Sensitive allele specific real time PCR for detection of HLAB*27 genotype
  • Inclusion of endogenous control as a quality check for whole procedure
  • Easy workflow with ready-to-use solutions and optimal quality control
  • Simple reaction setup and data interpretation
  • Includes all reagent required to perform Sample to Result analysis no additional reagents needed.
  • Low contamination risk – no post-PCR product handling
  • High-throughput – can screen up to 90 samples in a single run
  • Fast – results within 80 minutes after PCR start

Kit Contents

  • Reagents for nucleic acid extraction
  • Reagents for real time PCR
  • Quality Controls